AN: If anyone found this offensive or any way transphobic, please tell me!

"Are you sure about this?" Kara asked, scooting away as Alex approached her with the Kryptonite needle.

"Absolutely!" Alex replied. "Besides, you did agree that you would, if you didn't win the bet!"

"How could I forget?" Kara asked sarcastically.

"Don't know!" Alex shrugged cheerfully, then without further ado, she jabbed Kara's arm with the needle.

A few minutes later, a buff new superhero could be seen roaming through the DEO HQ.

"Is it Superman?" some of the agents of DEO asked themselves, for the figure amongst them wore the trademark Super outfit and had a very masculine, muscled cut, but there was something off about all of it. For one, this new Super had shaggy blond hair and crystal blue eyes. The Superman they knew, the one that hailed from Metropolis, had black hair and brown eyes. So who was this new guy?

"Don't ask," the mysterious superhero muttered as he shuffled past. Behind him, Alex Danvers was following after and snickering.

"J'onn?" the new superhero shoved open the door to J'onn's office. J'onn looked up at him in surprise.

"Who are you?" he asked. He, like the other DEO agents, saw and recognized the Super suit, but not the wearer. The face was large and sharp, handsome and smooth. There was something vaguely familiar about it, but J'onn wasn't quite sure...

"It's me!" the superhero replied, voice deep and low. "Kara Danvers!" for a moment, there was only silence at J'onn gave his office's intruder a strange look, then he finally was able to formulate one single question:

"Wait, what?"

A few minutes later, J'onn was rubbing his temples.

"You mean to tell me that you stumbled upon a new form of Kryptonite and your first idea was to stab yourself in the arm with it to see what would happen?" he demanded. Why did his "children" have to be so reckless?

"It was Alex's idea!" Kara pointed an accusatory finger at Alex.

"But you must've said yes!" J'onn shot back.

"Ok, I did," Kara grumbled, crossing her arms over her pecs.

"But Alex, may I ask why you thought this was, in any way, a good idea?" J'onn turned his ire on the elder Danvers sister.

"Well, I had read about the Pink Kryptonite and wanted to know if it was true!" Alex replied.

"You mean you already knew what it would do?!" Kara interrupted angrily. "Alex! You said this would be new to both of us!"

"It was!" Alex replied, raising her hands as Kara glared at her.

"You mean you let her inject you with a substance when you didn't know what it would do?!" J'onn interrupted. He narrowed his eyes at Kara again. Realizing what she'd said, Kara suddenly became very interested in the floor of the office.

J'onn turned his exasperated expression back on Alex.

"May I ask how and why?" he demanded.

"I was reading up on the different types of Kryptonite that we knew of and I stumbled across Pink Kryptonite," Alex admitted. "I read that it had the power to cause a Kryptonian to change sexes..." J'onn heaved another sigh, looking back and forth between Alex and her new "brother", who was look quite uncomfortable in a male body.

"Is there any way to cure this?" he demanded and when Alex could only suggest time, both he and Kara buried their faces in their hands.

But, as it turned out, time was indeed the cure. It only took a few days, but once the last of the Pink Kryptonite was flushed out of Kara's system, she was restored to her female body. But for those few days in which Kara had a male body, life got very interesting. For one, nearly every citizen of National City mistook her for her cousin, or some new member of the Super family.

"Are you Superman?" a little boy had once asked Kara, and Kara had been uncertain about whether or not she should just play along and say yes, or admit to him that her stupid sister had accidently changed her female body into a male one. In the end, Kara had only given him an unreadable smile before flying away as fast as she could.

But it wasn't even just little kids that made this mistake. Even some adults did as well.

"Superman?!" Kara had come in to stop a bank robbery and the robbers and their victims all mistook Kara for her cousin.

"Ain't you supposed to be in Metropolis?!" the leader of the robbers demanded of Kara when she closed in on him. Kara didn't reply verbally. Instead, she only gave him a pained smile before freezing him and his buddies in place with her ice breath. At least her powers still worked. But then the cops had come. When they caught an eyeful of Kara's new body, they were equally confused.

"Superman? Where is Supergirl?" they asked.

"It's a long story," she replied uncomfortably. The cops looked up at the male-bodied superhero in confusion, but when it became clear that Kara wasn't going to explain any further, they decided to let the issue drop and, instead, they returned to their task at hand: arresting the bank robbers.

Meanwhile, all the people Kara had saved were all clamoring to know who she was.

"Are you a new Super?" a woman asked.

"Or are you Superman in disguise?" a man asked.

"Does Supergirl have a brother?" one of the bank tellers asked.

"Does Superman?" another teller asked.

"Or are you Supergirl's boyfriend?" someone's child asked excitedly.

Although Kara found all these demanding questions to be quite stifling, she had to admit that the last one at least made her laugh. All of them were a strange mix of funny and painfully inaccurate, but the idea of being Supergirl's boyfriend amused her so much that she almost considered going with that idea. Almost. But then she realized it probably wouldn't be wise to start rumors about herself, so she left all of these questions unanswered. Instead, she only saluted them all a farewell before flying back to the safety of the DEO as fast as she could.

But speaking of Superman, when he caught wind of what had happened to her, he had wasted no time in teasing her about it...

"I always wanted a brother!" he told Kara over the phone. "I am sure you look so handsome! Not handsome as me, of course, but..."

"Shut it, Kal," Kara had replied.

"I'm just saying," he joked. "And hey, if National City needs Supergirl back, just send me some of that pink stuff. I'm sure I could-"

"That's not funny, Kal!" Kara interrupted him.

"I'm just trying to help the other last son of Krypton!" Superman defended. He managed to hear Kara groan in frustration over his own laughter.

"Get bent," she snapped, then she hung up on him and blocked him, silently vowing that until she could call herself the Girl of Steel again, the Man of Steel was going to stay on that blocked list. Stupid Kal. Superman, meanwhile, was still in stitches. Lois was going to get a kick out of this!

But Superman wasn't the only one who liked to tease Kara about her predicament.

"You're so handsome and muscled!" Winn joked as he felt Kara's giant biceps.

"You look just like your cousin!" James added. "I'm sure he'd be so proud of you!"

"I just hope National City doesn't miss Supergirl too much!" Winn agreed.

"I hate both of you," Kara replied, shoving Winn off of her. She was now taller than he was, and in fact, she even had about two inches on James!

"By the way, I love your tie!" James snickered as Winn fell over. "Tell me where you got it."

"Get bent!" Kara replied, crossing her arms.

That was another thing Kara had been forced to contend with. Even though her condition was slated only to last a few days, it wasn't like she could just vanish off the face of the Earth for those few days. Instead, she was pretty much forced to come up with some excuse as to why the "real" Kara Danvers was out, then adapt to living with a male body until the Pink Kryptonite would wear off. One of the things that came along with having to live in this new male form was the necessitation of new clothing. All of Kara's own, old clothing was too small now. This meant she'd had to borrow James'. She was wearing one of his suits and his ties, hence his mocking joke about where she'd gotten the tie.

Then, along with the new clothes, Kara had also come up with a new name. She was no longer Kara Danvers, but Karl Elzor, a temporary replacement for the real Kara Danvers until she got back. Suffice to say, Cat hadn't been too pleased for this new Karl fellow to just waltz into her office and take a seat at Kara's cubicle, but with James and Winn both helping Karl to explain why he was here, Cat decided to allow him to stay.

"I'm going to have to have some serious words with that girl when she gets back from her little trip!" the owner of CatCo muttered under her breath as Karl awkwardly fled from her presence. So while Kara Danvers was out on unspecified leave, Karl was here to pick up the slack.

"And he's hating every minute of it!" Kara grouched as she sat down at her computer, suddenly feeling too big for the chair. Winn and James continued to bite back laughter as they watched her go, still stewing about her predicament. They were never going to let her live that name down.

Only one person in all of the city had been able to recognize Kara at once, but it was still an embarrassing moment nonetheless.

"Supergirl!?" it was Lena Luthor.

"Yeah. Hi," Supergirl replied, voice deep and low as she flew into Lena's office. She really hadn't wanted to run into Lena while still in this form, but duty called, so she went.

"Uhhhh?" Lena tried not to stare too hard at Supergirl's much-taller, wider new body. Or the slight stubble already appearing on her chin. Or the fact that her once-long, wavy hair had somehow reshaped itself into a slightly shorter, shaggier, and more masculine hairstyle.

"Bad run-in with a rare type of Kryptonite," she grouched. "Don't ask. Just go with it."

"Well. Ok. Then," Lena blinked. Although Lena knew that National City could be weird, especially with its high alien population, this was definitely not something she'd ever seen before. She couldn't help but stare at Supergirl's new form and wonder... This was beyond strange. What kind of Kryptonite would ever do this?! Lex certainly never had turned Superman into a female, as far as she could recall. This was definitely new. And Lena, messed up as this was to say, was kind of disappointed by it. Supergirl's female physique was quite attractive to her, so this change displease Lena to some degree, but the longer Lena stared at Supergirl's new body, the more she began to wonder if she could possibly be bi...

At one point, Kara had considered just wearing a mask until she went back to normal, but then Alex pointed out that it wouldn't work.

"They'll still see your Super suit and your incredibly muscular form and make the same assumptions they did before," she said.

"Point taken," Supergirl grumbled, ditching her mask before flying off to stop another crime. Like before, criminal and victim alike could only stare in shock and confusion as this new Super descended down from above, and they could only ask where their Supergirl was.

"It's a long story, but she's fine," Supergirl said as she escorted the civilians to safety. "I'm standing in for her for a few days, but she'll be back soon, and I promise you everything will be normal by the end of the week!"

"But who are you?" one of the civilians pleaded. Supergirl pretended not to hear, flying away again not long after the last person made it to safety.

But in time, Kara returned to her old self and, with great relief, she took her old body back again.

"Thank Rao!" she cried as she felt her body begin to shift back into what it used to be. Supergirl was back in National City! She would deal with all the confusion about where she'd been later. Now, she was just going to revel in this moment! But now that Kara was back to normal, she began to ponder Pink Kryptonite with a more open mind. She still vowed that she would never take it again, but she began to wonder...

"Do you think Pink Kryptonite could ever be used for transgender aliens?" Kara asked. Though she had a special level of hatred for the pink crystals now, she still wasn't blind to all of its potentials.

"Maybe," Alex and J'onn both seemed reluctant to create more of the Pink Kryptonite, but after Kara's suggestion, they did decide to begin testing on whether or not it could be mass-produced and whether or not different lifeforms could use it, or if it was only Kryptonian. But, whenever testing was done around Pink Kryptonite, Kara made sure to steer clear of the labs.

"You sure you don't wanna test it again?" Alex teased one day, waving another needle playfully at Kara.

"Get bent!" Kara replied, but she got her revenge on Alex that night. Alex went to bed like normal, but woke up with a far different physical form.

"Kara!" a deep voice echoed through the small Danvers apartment, but Kara was already gone, laughing from a very safe, very far distance away from her "new brother".

AN: According to wiki, Pink Kryptonite can also change a Kryptonian's sex, it's just not as well-known or famous as the "it turns them gay" power. Also, if anyone found this offensive or any way transphobic, please tell me!