Sequel to Holding on and Letting Go. Cristina and Owen navigate the perils of addiction, recovery, and disability as their kids grow. Challenging new cases and relationship woes plague the hospital. Cristina jeopardizes her marriage and her career with a terrible secret. Collin grapples with problems from the past. Henry fights an uphill battle for survival.

Grey Sloan Memorial survives- fighting tooth and nail- it's what they do. And when the doctors start to leave the hospital as it becomes clear that no one from Grey Sloan will ever win a Harper Avery, Cristina Yang steps in to keep the hospital alive. Because that's what they do- they survive.

Follow the epic romance of Cristina and Owen from the earliest days to the inevitable downfall of their marriage; the dark memories between them and the warmth of friendship and companionship; follow them into the unpredictable future as they tackle parenthood; experience the rise, climax, fall, and rekindling of a truly great love.